TARGET partners, the Liverpool University Hospitals NHS Foundation Trust and the Liverpool Centre for Cardiovascular Science launched a new project aimed at developing an internationally recognised Core Outcome Set (COS), which will define clinically relevant outcomes to be used in future medical and scientific studies on New Onset Atrial Fibrillation (NOAF).

This project represents a valuable opportunity for TARGET stakeholders, as it primarily seeks to establish a clear and unified foundation for research in the specific field of atrial fibrillation (AF), one of the most common forms of cardiac arrhythmia. Despite its prevalence, this field remains marked by significant inefficiencies and often inadequate care for the most severely affected patients, who face a heightened risk of morbidity and mortality. In this context, medical and scientific research plays a vital role in promoting patient well-being and enhancing the quality of clinical care.

To gather sufficient data, the NHS and the Liverpool Centre for Cardiovascular Science are conducting a Delphi study based on the distribution of three questionnaires to medical and cardiology experts and researchers, including doctors, nurses, and healthcare professionals working in intensive care units with patients affected by serious cardiovascular conditions. The questionnaires are also directed toward patients living with atrial fibrillation (AF) or those who have previously been admitted to the intensive or critical care unit, as their lived experiences can offer valuable insights.

The study specifically involves two online surveys and one or two virtual meetings to discuss NOAF and reach a consensus on which outcomes should be prioritised in future clinical research.

To standardise results, minimise inconsistencies across studies in this specific area, and provide clearer guidance on effective interventions, broad and active community participation in this study is essential, as volunteer contributions will be crucial in advancing scientific research—particularly in the field of biomedical studies targeting the treatment of New Onset Atrial Fibrillation.

This initiative is funded by the National Institute for Health and Care Research (NIHR) and has received ethical approval from the University of Liverpool. It is also registered with the COMET Initiative, and the study protocol is published in BMJ Open.

If you are interested in participating, please complete the online form at the following link:
⭢ https://forms.office.com/e/daxRRf4UNX

For more information on how to get involved, please download the flyer here or contact the responsible partners at: cos-abacus@liverpoolft.nhs.uk